Molecular Design Lab

Publications

Research on excited-state mechanisms, fluorophores, photostability, and molecular design. Explore papers, preprints, and research data.

All research outputs. Conference activities are listed under Updates.

  1. 2026 · Nature Chemistry

    A general strategy towards multicolour fluorogenic peptides for wash-free bioassays ↗

    Wong, Man Sing; Mendive-Tapia, Lorena; Karmakar, Utsa; Vashist, Lovelesh; Nare, Zandile; Tokarczyk, Karolina; Iijima, Kohei; Kikuchi, Kazuya; Abedi, Syed Ali Abbas; Liu, Xiaogang; Vendrell, Marc

    BibTeX citation
    @article{pub37,
      output_type = {article},
      title = {A general strategy towards multicolour fluorogenic peptides for wash-free bioassays},
      author = {Wong, Man Sing and Mendive-Tapia, Lorena and Karmakar, Utsa and Vashist, Lovelesh and Nare, Zandile and Tokarczyk, Karolina and Iijima, Kohei and Kikuchi, Kazuya and Abedi, Syed Ali Abbas and Liu, Xiaogang and Vendrell, Marc},
      journal = {Nature Chemistry},
      year = {2026},
      doi = {10.1038/s41557-026-02228-0},
      html = {https://doi.org/10.1038/s41557-026-02228-0},
      selected = {true}
    }
    
  2. 2026 · Zenodo / DR-NTU (Data) · Dataset

    A Computational Workflow for Uncovering Photoinduced Electron Transfer Mechanisms in Fluorescent Molecules ↗

    Abedi, Syed Ali Abbas; Lovelesh; Chi, Weijie; Liu, Xiaogang

    BibTeX citation
    @misc{pub0,
      output_type = {dataset},
      title = {A Computational Workflow for Uncovering Photoinduced Electron Transfer Mechanisms in Fluorescent Molecules},
      author = {Abedi, Syed Ali Abbas and Lovelesh and Chi, Weijie and Liu, Xiaogang},
      journal = {Zenodo / DR-NTU (Data)},
      year = {2026},
      html = {https://zenodo.org/records/17374292},
      selected = {false}
    }
    
  3. 2026 · Chemical Society Reviews

    Mechanistic insights into the design of fluorogenic molecules for wash-free biological applications ↗

    Huang, R; Abedi, SAA; Jiang, G; Wang, C; Peng, L; Shen, T; Mroweh, N

    BibTeX citation
    @article{pub1,
      output_type = {article},
      preview = {1.jpg},
      title = {Mechanistic insights into the design of fluorogenic molecules for wash-free biological applications},
      selected = {true},
      author = {Huang, R and Abedi, SAA and Jiang, G and Wang, C and Peng, L and Shen, T and Mroweh, N},
      journal = {Chemical Society Reviews},
      year = {2026},
      html = {https://pubs.rsc.org/ko/content/articlelanding/2026/cs/d5cs01519g}
    }
    
  4. 2026 · Advanced Optical Materials

    Red and Robust: Highly Stable Electrofluorochromic Switching in Cyano‐Substituted Aggregation‐Induced Emission‐Active Conjugated Polymers ↗

    Hui, B. Y. K.; Tao, R.; Chin, K. L. O.; Soo, X. Y. D.; Sng, A.; Abedi, S. A. A.; Chong, K. C.; Liu, X.; Xu, J.; Chua, M. H.

    BibTeX citation
    @article{pub3,
      output_type = {article},
      preview = {3.jpg},
      title = {Red and Robust: Highly Stable Electrofluorochromic Switching in Cyano‐Substituted Aggregation‐Induced Emission‐Active Conjugated Polymers},
      selected = {true},
      author = {Hui, B. Y. K. and Tao, R. and Chin, K. L. O. and Soo, X. Y. D. and Sng, A. and Abedi, S. A. A. and Chong, K. C. and Liu, X. and Xu, J. and Chua, M. H.},
      journal = {Advanced Optical Materials},
      year = {2026},
      html = {https://advanced.onlinelibrary.wiley.com/doi/10.1002/adom.202502075}
    }
    
  5. 2025 · Nature Methods

    Super-photostable organic dye for long-term live-cell single-protein imaging ↗

    Kim, D. H.; Triet, H. M.; Lee, S. H.; Jazani, S.; Jang, S.; Abedi, S. A. A.; Liu, X.; Seo, J.; Ha, T.; Chang, Y. T.; Ryu, S. H.

    BibTeX citation
    @article{pub4,
      output_type = {article},
      preview = {4.jpg},
      title = {Super-photostable organic dye for long-term live-cell single-protein imaging},
      author = {Kim, D. H. and Triet, H. M. and Lee, S. H. and Jazani, S. and Jang, S. and Abedi, S. A. A. and Liu, X. and Seo, J. and Ha, T. and Chang, Y. T. and Ryu, S. H.},
      journal = {Nature Methods},
      year = {2025},
      html = {https://www.nature.com/articles/s41592-024-02584-0}
    }
    
  6. 2025 · Chinese Chemical Letters

    “Superimposed” spectral characteristics of fluorophores arising from cross-conjugation hybridization ↗

    An, K; Qiao, Q; Abedi, SAA; Liu, X; Xu, Z

    BibTeX citation
    @article{pub5,
      output_type = {article},
      preview = {5.jpg},
      title = {“Superimposed” spectral characteristics of fluorophores arising from cross-conjugation hybridization},
      author = {An, K and Qiao, Q and Abedi, SAA and Liu, X and Xu, Z},
      journal = {Chinese Chemical Letters},
      year = {2025},
      html = {https://www.sciencedirect.com/science/article/abs/pii/S100184172400305X}
    }
    
  7. 2025 · Journal of the American Chemical Society

    "Clicked" Hydrazone Photoswitches ↗

    Sosnin, D.; Izadyar, M.; Abedi, S. A. A.; Liu, X.; Aprahamian, I.

    BibTeX citation
    @article{pub6,
      output_type = {article},
      preview = {6.jpg},
      title = {"Clicked" Hydrazone Photoswitches},
      author = {Sosnin, D. and Izadyar, M. and Abedi, S. A. A. and Liu, X. and Aprahamian, I.},
      journal = {Journal of the American Chemical Society},
      year = {2025},
      html = {https://pubs.acs.org/doi/abs/10.1021/jacs.5c02183}
    }
    
  8. 2025 · CCS Chemistry

    Oxazolidine-Caged Heptamethine Cyanine Switch Exhibits High Photostability for Bioimaging via Buffering Fluorogenicity ↗

    Qi, Q.; Li, J.; Qiao, Q.; Yan, C.; Izadyar, M.; Wang, C.; Abedi, S. A. A.; Liu, X.; Guo, Z.; Xu, Z.

    BibTeX citation
    @article{pub7,
      output_type = {article},
      preview = {7.jpg},
      title = {Oxazolidine-Caged Heptamethine Cyanine Switch Exhibits High Photostability for Bioimaging via Buffering Fluorogenicity},
      author = {Qi, Q. and Li, J. and Qiao, Q. and Yan, C. and Izadyar, M. and Wang, C. and Abedi, S. A. A. and Liu, X. and Guo, Z. and Xu, Z.},
      journal = {CCS Chemistry},
      year = {2025},
      html = {https://www.chinesechemsoc.org/doi/full/10.31635/ccschem.025.202405383}
    }
    
  9. 2025 · Advanced Functional Materials

    Moisture Tolerance, Thermally Stable and Light Switchable Adhesives Platform Based on Reversible Redshifted [2+ 2] Photocycloaddition ↗

    Oh, X. Y.; Thi, Q. V.; Yu, M. M. L.; Izadyar, M.; Abedi, S. A. A.; Liu, X.; Truong, V. X.

    BibTeX citation
    @article{pub8,
      output_type = {article},
      preview = {8.jpg},
      title = {Moisture Tolerance, Thermally Stable and Light Switchable Adhesives Platform Based on Reversible Redshifted [2+ 2] Photocycloaddition},
      author = {Oh, X. Y. and Thi, Q. V. and Yu, M. M. L. and Izadyar, M. and Abedi, S. A. A. and Liu, X. and Truong, V. X.},
      journal = {Advanced Functional Materials},
      year = {2025},
      html = {https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202421823}
    }
    
  10. 2025 · Angewandte Chemie

    Hetero‐Hydrazone Photoswitches ↗

    Sosnin, D.; Abedi, S. A. A.; Izadyar, M.; Ünal, Y.; Liu, X.; Aprahamian, I.

    BibTeX citation
    @article{pub9,
      output_type = {article},
      preview = {9.jpg},
      title = {Hetero‐Hydrazone Photoswitches},
      author = {Sosnin, D. and Abedi, S. A. A. and Izadyar, M. and Ünal, Y. and Liu, X. and Aprahamian, I.},
      journal = {Angewandte Chemie},
      year = {2025},
      html = {https://onlinelibrary.wiley.com/doi/abs/10.1002/ange.202515136}
    }
    
  11. 2025 · Angewandte Chemie

    Unveiling the Power of Dark State Photocages: An Efficient Pathway to Triplet State under Near‐Infrared Light Irradiation ↗

    Hu, Q.; Du, J.; Abedi, S. A. Abbas; Liu, X.; Long, S.; Sun, W.; Fan, J.; Peng, X.

    BibTeX citation
    @article{pub10,
      output_type = {article},
      preview = {10.jpg},
      title = {Unveiling the Power of Dark State Photocages: An Efficient Pathway to Triplet State under Near‐Infrared Light Irradiation},
      author = {Hu, Q. and Du, J. and Abedi, S. A. Abbas and Liu, X. and Long, S. and Sun, W. and Fan, J. and Peng, X.},
      journal = {Angewandte Chemie},
      year = {2025},
      html = {https://onlinelibrary.wiley.com/doi/abs/10.1002/ange.202504670}
    }
    
  12. 2025 · Materials Chemistry Frontiers

    Highly stable electrofluorochromic switching of aggregation-induced emission-active conjugated polymers ↗

    Tao, R.; Hui, B. Y. K.; Chin, K. L. O.; Soo, X. Y. D.; Zhang, D.; Abedi, S. A. A.; Bi, P.; Liu, X.; Xu, J.; Chua, M. H.

    BibTeX citation
    @article{pub11,
      output_type = {article},
      preview = {11.jpg},
      title = {Highly stable electrofluorochromic switching of aggregation-induced emission-active conjugated polymers},
      author = {Tao, R. and Hui, B. Y. K. and Chin, K. L. O. and Soo, X. Y. D. and Zhang, D. and Abedi, S. A. A. and Bi, P. and Liu, X. and Xu, J. and Chua, M. H.},
      journal = {Materials Chemistry Frontiers},
      year = {2025},
      html = {https://pubs.rsc.org/en/content/articlehtml/2025/qm/d5qm00035a}
    }
    
  13. 2025 · Chinese Chemical Letters

    Barrierless conical intersection as a photophysical design principle for photoacoustic and photothermal contrast agents ↗

    Wu, Z.; Abedi, S. A. A.; Huang, R.; Lin, L.; Liu, X.

    BibTeX citation
    @article{pub12,
      output_type = {article},
      preview = {12.jpg},
      title = {Barrierless conical intersection as a photophysical design principle for photoacoustic and photothermal contrast agents},
      author = {Wu, Z. and Abedi, S. A. A. and Huang, R. and Lin, L. and Liu, X.},
      journal = {Chinese Chemical Letters},
      year = {2025},
      html = {https://www.sciencedirect.com/science/article/abs/pii/S1001841725014925}
    }
    
  14. 2024 · Advanced Science

    Aryl-Modified Pentamethyl Cyanine Dyes at the C2’Position: A Tunable Platform for Activatable Photosensitizers ↗

    Han, F.; Abedi, S. A. A.; He, S.; Zhang, H.; Long, S.; Zhou, X.; Chanmungkalakul, S.; Ma, H.; Sun, W.; Liu, X.; Du, J.; Fan, J.; Peng, X.

    BibTeX citation
    @article{pub13,
      output_type = {article},
      preview = {13.jpg},
      title = {Aryl-Modified Pentamethyl Cyanine Dyes at the C2’Position: A Tunable Platform for Activatable Photosensitizers},
      author = {Han, F. and Abedi, S. A. A. and He, S. and Zhang, H. and Long, S. and Zhou, X. and Chanmungkalakul, S. and Ma, H. and Sun, W. and Liu, X. and Du, J. and Fan, J. and Peng, X.},
      journal = {Advanced Science},
      year = {2024},
      html = {https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202305761}
    }
    
  15. 2024 · Dyes and Pigments

    Solvatochromic fluorescent ethynyl naphthalimide derivatives for detection of water in organic solvents ↗

    Nhu, QPN; Abedi, SAA; Chanmungkalakul, S; Sukwattanasinitt, M

    BibTeX citation
    @article{pub14,
      output_type = {article},
      preview = {14.jpg},
      title = {Solvatochromic fluorescent ethynyl naphthalimide derivatives for detection of water in organic solvents},
      author = {Nhu, QPN and Abedi, SAA and Chanmungkalakul, S and Sukwattanasinitt, M},
      journal = {Dyes and Pigments},
      year = {2024},
      html = {https://www.sciencedirect.com/science/article/abs/pii/S0143720824002535}
    }
    
  16. 2024 · Chinese Chemical Letters

    The dark side of cyclooctatetraene (COT): photophysics in the singlet states of "self-healing" dyes ↗

    Chanmungkalakul, S.; Abedi, S. A. A.; Hernandez, F. J.; Xu, J.; Liu, X.

    BibTeX citation
    @article{pub15,
      output_type = {article},
      preview = {15.jpg},
      title = {The dark side of cyclooctatetraene (COT): photophysics in the singlet states of "self-healing" dyes},
      author = {Chanmungkalakul, S. and Abedi, S. A. A. and Hernandez, F. J. and Xu, J. and Liu, X.},
      journal = {Chinese Chemical Letters},
      year = {2024},
      html = {https://www.sciencedirect.com/science/article/abs/pii/S1001841723009786}
    }
    
  17. 2024 · CCS Chemistry

    Conformational Folding Activates Photoinduced Electron Transfer ↗

    Huang, S.; Abedi, S. A. A.; Li, Z.; Huang, R.; Yan, X.; Izadyar, M.; Qiao, Q.; Fang, Y.; Xu, Z.; Liu, X.

    BibTeX citation
    @article{pub16,
      output_type = {article},
      preview = {16.jpg},
      title = {Conformational Folding Activates Photoinduced Electron Transfer},
      author = {Huang, S. and Abedi, S. A. A. and Li, Z. and Huang, R. and Yan, X. and Izadyar, M. and Qiao, Q. and Fang, Y. and Xu, Z. and Liu, X.},
      journal = {CCS Chemistry},
      year = {2024},
      html = {https://www.chinesechemsoc.org/doi/full/10.31635/ccschem.024.202404541}
    }
    
  18. 2024 · SSRN · Preprint

    Solvent-Controlled GSIPT and TICT in a Schiff Base ↗

    Abedi, SAA; Yadav, P; Liu, X

    BibTeX citation
    @misc{pub25,
      output_type = {preprint},
      preview = {25.jpg},
      title = {Solvent-Controlled GSIPT and TICT in a Schiff Base},
      author = {Abedi, SAA and Yadav, P and Liu, X},
      journal = {SSRN},
      year = {2024},
      html = {https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4563845}
    }
    
  19. 2023 · Angewandte Chemie International Edition

    Janus‐Type ESIPT Chromophores with Distinctive Intramolecular Hydrogen‐bonding Selectivity ↗

    Chen, Y.; Lu, S.; Abedi, S. A. A.; Jeong, M.; Li, H.; Kim, M. H.; Park, S.; Liu, X.; Yoon, J.; Chen, X.

    BibTeX citation
    @article{pub27,
      output_type = {article},
      preview = {27.jpg},
      title = {Janus‐Type ESIPT Chromophores with Distinctive Intramolecular Hydrogen‐bonding Selectivity},
      author = {Chen, Y. and Lu, S. and Abedi, S. A. A. and Jeong, M. and Li, H. and Kim, M. H. and Park, S. and Liu, X. and Yoon, J. and Chen, X.},
      journal = {Angewandte Chemie International Edition},
      year = {2023},
      html = {https://onlinelibrary.wiley.com/doi/10.1002/anie.202311543}
    }
    
  20. 2023 · Angewandte Chemie International Edition

    The Highly Operational Team (HOT) toward f-Block Materials

    Park, KC; Kittikhunnatham, P; Lim, J; Thaggard, GC; Liu, Y; Martin, CR

    BibTeX citation
    @article{pub28,
      output_type = {article},
      preview = {28.jpeg},
      title = {The Highly Operational Team (HOT) toward f-Block Materials},
      author = {Park, KC and Kittikhunnatham, P and Lim, J and Thaggard, GC and Liu, Y and Martin, CR},
      journal = {Angewandte Chemie International Edition},
      year = {2023}
    }
    
  21. 2023 · Angewandte Chemie International Edition

    Blending Low‐Frequency Vibrations and Push–Pull Effects Affords Superior Photoacoustic Imaging Agents ↗

    Yu, L.; Abedi, S. A. A.; Lee, J.; Xu, Y.; Son, S.; Chi, W.; Li, M.; Liu, X.; Park, J. H.; Kim, J. S.

    BibTeX citation
    @article{pub29,
      output_type = {article},
      preview = {29.jpg},
      title = {Blending Low‐Frequency Vibrations and Push–Pull Effects Affords Superior Photoacoustic Imaging Agents},
      author = {Yu, L. and Abedi, S. A. A. and Lee, J. and Xu, Y. and Son, S. and Chi, W. and Li, M. and Liu, X. and Park, J. H. and Kim, J. S.},
      journal = {Angewandte Chemie International Edition},
      year = {2023},
      html = {https://onlinelibrary.wiley.com/doi/10.1002/anie.202307797}
    }
    
  22. 2022 · Chemical Communications

    A PET-based fluorescent probe for monitoring labile Fe (ii) pools in macrophage activations and ferroptosis ↗

    Xing, W.; Xu, H.; Ma, H.; Abedi, S. A. A.; Wang, S.; Zhang, X.; Liu, X.; Xu, H.; Wang, W.; Lou, K.

    BibTeX citation
    @article{pub33,
      output_type = {article},
      preview = {33.png},
      title = {A PET-based fluorescent probe for monitoring labile Fe (ii) pools in macrophage activations and ferroptosis},
      author = {Xing, W. and Xu, H. and Ma, H. and Abedi, S. A. A. and Wang, S. and Zhang, X. and Liu, X. and Xu, H. and Wang, W. and Lou, K.},
      journal = {Chemical Communications},
      year = {2022},
      html = {https://pubs.rsc.org/en/content/articlelanding/2022/cc/d1cc06611k/unauth}
    }
    
  23. 2022 · CCS Chemistry

    Rational design and application of an indolium-derived heptamethine cyanine with record-long second near-infrared emission ↗

    Ma, X.; Huang, Y.; Abedi, S. A. A.; Kim, H.; Davin, T.; Liu, X.; Yang, W. C.; Sun, Y.; Liu, S. H.; Yin, J.; Yoon, J.; Yang, G. F.

    BibTeX citation
    @article{pub34,
      output_type = {article},
      preview = {34.jpg},
      title = {Rational design and application of an indolium-derived heptamethine cyanine with record-long second near-infrared emission},
      author = {Ma, X. and Huang, Y. and Abedi, S. A. A. and Kim, H. and Davin, T. and Liu, X. and Yang, W. C. and Sun, Y. and Liu, S. H. and Yin, J. and Yoon, J. and Yang, G. F.},
      journal = {CCS Chemistry},
      year = {2022},
      html = {https://www.chinesechemsoc.org/doi/full/10.31635/ccschem.021.202101630}
    }
    
  24. 2021 · The Journal of Physical Chemistry A

    Restriction of Twisted Intramolecular Charge Transfer Enables the Aggregation-Induced Emission of 1-(N,N-Dialkylamino)-naphthalene Derivatives ↗

    Abedi, S. A. A.; Chi, W.; Tan, D.; Shen, T.; Wang, C.; Ang, E. C.; Tan, C. H.; Anariba, F.; Liu, X.

    BibTeX citation
    @article{pub35,
      output_type = {article},
      preview = {35.jpeg},
      title = {Restriction of Twisted Intramolecular Charge Transfer Enables the Aggregation-Induced Emission of 1-(N,N-Dialkylamino)-naphthalene Derivatives},
      author = {Abedi, S. A. A. and Chi, W. and Tan, D. and Shen, T. and Wang, C. and Ang, E. C. and Tan, C. H. and Anariba, F. and Liu, X.},
      journal = {The Journal of Physical Chemistry A},
      year = {2021},
      html = {https://doi.org/10.1021/acs.jpca.1c06263}
    }
    
  25. 2021 · Nature Communications

    Fluorescence umpolung enables light-up sensing of N-acetyltransferases and nerve agents ↗

    Yan, C.; Guo, Z.; Chi, W.; Fu, W.; Abedi, S. A. A.; Liu, X.; Tian, H.; Zhu, W. H.

    BibTeX citation
    @article{pub36,
      output_type = {article},
      preview = {36.webp},
      title = {Fluorescence umpolung enables light-up sensing of N-acetyltransferases and nerve agents},
      author = {Yan, C. and Guo, Z. and Chi, W. and Fu, W. and Abedi, S. A. A. and Liu, X. and Tian, H. and Zhu, W. H.},
      journal = {Nature Communications},
      year = {2021},
      html = {https://www.nature.com/articles/s41467-021-24187-5}
    }
    
  26. 2019 · Master’s thesis, Lahore University of Management Sciences · Thesis

    Predator-Prey Model with Age Structures ↗

    Abedi, Syed Ali Abbas

    BibTeX citation
    @misc{pub26,
      output_type = {thesis},
      preview = {26.jpg},
      title = {Predator-Prey Model with Age Structures},
      author = {Abedi, Syed Ali Abbas},
      journal = {Master's thesis, Lahore University of Management Sciences},
      year = {2019},
      html = {https://drive.google.com/file/d/1zfhP2b7VcZHInWiFsKtOuTnUw0lD240W/view?usp=sharing}
    }
    

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